Once phosphorylated and activated by PKA, hormone-sensitive lipase translocates to lipid droplets within the fat cell and begins breaking down stored triglycerides into free fatty acids and glycerol
For Asians, especially women with darker skin tones (Fitzpatrick Skin Types IV and V), clear, bright skin is considered highly desirable, and various topical, oral, or injection-based cosmetic skin-lightening agents with different mechanisms of action are widely available across Asia
Aconitase is one of several iron-sulfur-containing (de)hydratases in metabolic pathways shown to be inactivated by superoxide
The most widely discussed change is facial volume loss
However, published human pharmacokinetic data comparing oral to injectable absorption at equivalent doses has not been established in peer-reviewed literature
Its also important to be aware of possible side effects, such as ongoing nausea or serious injection-site reactions